Plastic circular economy in the EU: Material Flow Analysis and Transition Analysis

Plastic is valued for its versatility, but concerns have been raised over the environmental impacts of plastic waste. A more in-depth investigation of the plastic system is still needed to understand current flows and factors to close the plastic cycle. This research applied a material flow analysis (MFA) and transition analysis (TA), using multilevel perspectives, to the plastic circular economy transition in the EU. The MFA covers over 400 categories of plastic-containing products with a detailed analysis of the final destination of waste. The TA identifies the interaction of barriers and drivers to use secondary plastics, with a focus on the regime level along the plastic value chain. The MFA results indicate the EU produced over 66  million tonnes (Mt) of plastic polymers/fibres and an estimated consumption for plastic products of 73 Mt in 2016. Plastic waste increases amounted to over 37 Mt, and a significant amount of plastic waste was not recovered back into plastics in the EU. The uncertainty analysis of MFA highlights important data quality issues that need to be addressed. To understand why using secondary plastics presents challenges, the TA mapped the factors across policies and standards, markets and business models, technology, and consumer preferences and behaviours that create a web of constraints and a web of drivers. TA results highlight that data-information-knowledge is the key gap as most of the aspects are cross-cutting. Different actors are involved in new business networks and play multiple roles in driving the co-evolutionary dynamic. The thesis concludes that significant data gaps need MFA-based knowledge to inform policies that address the barriers and the potential socio-technical changes that can reshape plastic flows. The cases playing out across the whole value chain and four different application areas provide insights that are potentially more widely applicable to the circular economy transition processes in Europe

Closing the loop on plastics in Europe: The role of data, information and knowledge

Concerns over plastic waste and support for a plastic circular economy have been growing in recent years. Specific needs to promote re-circulation of plastics in terms of data, information and knowledge are poorly understood. Based on the multi-level perspective on socio-technical transitions and semi-structured interviews with key stakeholders, this paper aims to understand how information and knowledge issues may inhibit or foster the development of secondary plastics markets in Europe. Results highlight that key barriers associated with data-information-knowledge map across, and interact with, policies and standards, market and technology, socio-cultural norms, networks and business models. The packaging sector has drawn more policy attention, and institutions to support information sharing such as labelling and certification are more mature. The automotive and EEE sectors have illustrated knowledge diffusion through supply chain collaboration, while the construction sector appears to have slower practical progress on industry-level knowledge diffusion. This paper contributes to the multi-level perspective on transition studies by focusing the empirical work on a new area of plastic circular economy. The cases playing out across the whole value chain and four different application areas provide insights that are potentially more widely applicable to the circular economy transition processes in Europe

Interfacial Properties of Polyethylene Glycol/Vinyltriethoxysilane (PEG/VTES) Copolymers and their Application to Stain Resistance

In this study, polyethylene glycol (PEG) and vinyltriethoxysilane (VTES) were used in different proportions to produce a series of PEG–VTES copolymers. The copolymer molecular structures were confirmed by FTIR spectroscopy. In addition, their surface activities were evaluated by evaluating the surface tension, contact angle, and foaming properties. The results showed that these surfactants exhibited excellent surface activities and wetting power, as well as low foaming. Consequently, the application of a series of PEG/VTES copolymers can make cotton fabrics stain resistant

Functional Effects of let-7g Expression in Colon Cancer Metastasis.

MicroRNA regulation is crucial for gene expression and cell functions. It has been linked to tumorigenesis, development and metastasis in colorectal cancer (CRC). Recently, the let-7 family has been identified as a tumor suppressor in different types of cancers. However, the function of the let-7 family in CRC metastasis has not been fully investigated. Here, we focused on analyzing the role of let-7g in CRC. The Cancer Genome Atlas (TCGA) genomic datasets of CRC and detailed data from a Taiwanese CRC cohort were applied to study the expression pattern of let-7g. In addition, in vitro as well as in vivo studies have been performed to uncover the effects of let-7g on CRC. We found that the expression of let-7g was significantly lower in CRC specimens. Our results further supported the inhibitory effects of let-7g on CRC cell migration, invasion and extracellular calcium influx through store-operated calcium channels. We report a critical role for let-7g in the pathogenesis of CRC and suggest let-7g as a potential therapeutic target for CRC treatment

Production of Active Nonglycosylated Recombinant B-Chain of Type-2 Ribosome-Inactivating Protein from Viscum articulatum and Its Biological Effects on Peripheral Blood Mononuclear Cells

Type-2 ribosome-inactivating proteins, composed of a toxic A-chain and lectin-like B-chain, display various biological functions, including cytotoxicity and immunomodulation. We here cloned the lectin-like B-chain encoding fragment of a newly identified type-2 RIP gene, articulatin gene, from Viscum articulatum, into a bacterial expression vector to obtain nonglycosylated recombinant protein expressed in inclusion bodies. After purification and protein refolding, soluble refolded recombinant articulatin B-chain (rATB) showed lectin activity specific toward galactoside moiety and was stably maintained while stored in low ionic strength solution. Despite lacking glycosylation, rATB actively bound leukocytes with preferential binding to monocytes and in vitro stimulated PBMCs to release cytokines without obvious cytotoxicity. These results implicated such a B-chain fragment as a potential immunomodulator

Extracorporeal membrane oxygenation for neonatal congenital diaphragmatic hernia: The initial single-center experience in Taiwan

Background/Purpose Extracorporeal membrane oxygenation (ECMO) is a treatment option for stabilizing neonates with congenital diaphragmatic hernia (CDH) in a critical condition when standard therapy fails. However, the use of this approach in Taiwan has not been previously reported. Methods The charts of all neonates with CDH treated in our institute during the period 2007–2014 were reviewed. After 2010, patients who could not be stabilized with conventional treatment were candidates for ECMO. We compared the demographic data of patients with and without ECMO support. The clinical course and complications of ECMO were also reviewed. Results We identified 39 neonates with CDH with a median birth weight of 2696 g (range, 1526–3280 g). Seven (18%) of these patients required ECMO support. The APGAR score at 5 minutes differed significantly between the ECMO and non-ECMO groups. The survival rate was 84.6% (33/39) for all CDH patients and 57.1% (4/7) for the ECMO group. The total ECMO bypass times in the survivors was in the range of 5–36 days, whereas all nonsurvivors received ECMO for at least 36 days (mean duration, 68 days). Surgical bleeding occurred in four of seven patients in the ECMO group. Conclusion The introduction of ECMO rescued some CDH patients who could not have survived by conventional management. Prolonged (i.e., > 36 days) ECMO support had no benefit for survival